British Society for Allergy and Immunology Abstracts From the 2024 Annual Conference
pulmonary asthma :: Article Creator Asthma In Children And Pollution: NO2 Exposure May Affect Treatment Response Some asthma therapy appeared to be less effective in Black children living in areas with high levels of nitrogen dioxide (NO2), according to study findings published in the Journal of Allergy and Clinical Immunology. Researchers assessed the effect of air pollutants on asthma treatments, using data from the randomized Best African American Response to Asthma Drugs (BARD) trial (ClinicalTrials.Gov Identifier: NCT01967173). The trial enrolled 280 children aged 5 to 11 years with inadequately controlled asthma using low-dosage corticosteroids, with children assigned to a random sequence of commonly prescribed treatments of baseline low inhaled corticosteroids (ICS) dose, double ICS with long-acting beta-agonists (2×ICS+LABA), quintuple ICS (5×ICS), and quintuple ICS with LABA (5×ICS+LABA) for 14 weeks per treatment regimen. The current ancill...